Preface

This book presents steps for phenotyping survival outcomes using data from UK Biobank (UKB) study (Sudlow 2015). The following are the outcomes we phenotyped:

Diabetes
Myocardial Infarction
Unstable Angina
Ischemic Stroke
Hemorrhagic Stroke
Stroke
Percutaneous Coronary Intervention (PCI)
Composite cardiovascular disease (CVD)
Diabetic Eye Disease or Diabetic Retinopathy (DR)
Chronic/Diabetic Kidney Disease (CKD/DKD)

We will refer UKB assessment center data as “UKB data” and the associated primary care data as “UKB primary care data.” These two sources of data will be prepared separately and then combined to create event tables for various outcomes. These tables will then be used to phenotype survival traits.

References

Sudlow, John AND Allen, Cathie AND Gallacher. 2015. “UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age.” PLOS Medicine 12 (3): 1–10. https://doi.org/10.1371/journal.pmed.1001779.